What is ABECMA? ABECMA (idecabtagene vicleucel) is a prescription medicine for the treatment of multiple myeloma in patients who have received at least four kinds of treatment regimens that have not worked or have stopped working. ABECMA is a medicine made from your own white blood cells; the cells are genetically modified to recognize and attack your multiple myeloma cells.

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Not an actual patient.

Your one-time infusion* of ABECMA®

A treatment process you can depend on

There are 6 steps
to treatment
with ABECMA:

6 Steps of Abecma treatment process

Every patient is different, and the time it takes to complete the ABECMA treatment process may vary.

ABECMA comes with the risk for severe or life-threatening side effects. It is only available at certified treatment centers and must be infused by trained healthcare teams. Your doctor will refer you to a certified treatment center to be evaluated for treatment if you aren’t already at one.

What happens during each step
of the ABECMA treatment

  • Step 1: Blood collection (apheresis)

    Your immune cells will be collected through a process called apheresis (sometimes called leukapheresis)
    • Your blood is collected (each of the components is separated into groups)
    • Your T cells are removed (the other parts of your blood are returned back into your body)
    • Apheresis can be done in 1 day and usually takes 2 to 6 hours
  • Step 2: CAR T cell creation

    After your T cells are collected, they are sent to a specialized manufacturing laboratory to be made
    into ABECMA

    At the specialized manufacturing laboratory:

    • “Hooks” called CARs are added to your T cells, creating ABECMA that is unique to you
    • After your ABECMA is created, your cells are multiplied
    • This process takes about 4 weeks, but every patient’s cells are different and process times may vary

    Your healthcare provider may also recommend other treatments to manage your multiple myeloma while your ABECMA is created and multiplied.

    CARs=chimeric antigen receptors.

  • Step 3: Pre-infusion treatment

    Shortly before your ABECMA infusion, you’ll receive short-course chemotherapy for 3 days
    • Short-course chemotherapy (3 days) helps prepare your body for ABECMA
    • This type of chemotherapy is composed of 2 medications and is given to all patients who receive ABECMA
  • Step 4: One-time infusion of ABECMA

    You’ll receive ABECMA as a one-time intravenous infusion
    • Your ABECMA infusion will take place at a certified treatment center by your trained healthcare team
    • Your ABECMA infusion usually takes up to 30 minutes for each infusion bag
  • Step 5: Follow-up monitoring

    You’ll be closely monitored for side effects following your ABECMA infusion
    • You will be monitored at least daily for 7 days after the infusion
    • Plan to stay close to the treatment center (within 2 hours) for at least 4 weeks after infusion so your healthcare team can help you with any side effects that may occur
  • Step 6: Long-term follow-up

    You’ll follow up with your healthcare team after at least 4 weeks of initial monitoring
    • You and your healthcare team will work together to track your progress, including monitoring for potential side effects
    • Additional scans and blood tests may also be needed
    • Your long-term care, which will continue after treatment center monitoring, may be overseen by the healthcare provider who originally referred you

*The treatment process includes blood collection, CAR T cell creation, administration, and adverse event monitoring.
There is a risk of manufacturing failure. In the ABECMA clinical trial, 2 out of 135 patients were impacted. Speak to your doctor for more information.
Your dose of ABECMA may be given in one or more infusion bags.